Introduction (Article introduction authored by ICU Editorial Team) Sepsis, characterized by life-threatening organ dysfunction due to a dysregulated host response to infection, affects millions worldwide annually and carries a high…
Introduction (Article introduction authored by ICU Editorial Team) Children and adolescents with severe neurological impairment (SNI) face complex medical challenges, often experiencing severe and recurrent lower respiratory tract infections (LRTIs).…
Introduction (Article introduction authored by ICU Editorial Team) Bacterial and fungal infections are prevalent among intensive care unit (ICU) patients, with up to 50% diagnosed at any given time. These…
Introduction Sepsis-Associated Acute Kidney Injury (SA-AKI) is a critical condition with high morbidity and mortality in intensive care unit patients. Extracorporeal blood purification therapies have been developed for managing sepsis…
Introduction Treatment options for infections caused by multidrug- resistant (MDR) Enterobacterales are limited and these infections are associated with high clinical failure and mortality rates, especially in vulnerable patients. In…
Introduction This article discusses community-acquired pneumonia (CAP), which accounts for approximately 2.2% of emergency department visits in the United States. Bacterial, viral, and fungal pathogens can cause infectious pneumonia, with…
Introduction Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered as indicators of either infection or…
Introduction Solid organ transplant (SOT) recipients in South Asia frequently contract fungi infections. After urinary tract infections and tuberculosis, invasive fungal infections (IFI) are the third most frequent cause of…
Introduction Invasive aspergillosis (IA) is an acute infection affecting patients who are immunocompromised, as a result of receiving chemotherapy for malignancy, or immunosuppressant agents for transplantation or autoimmune disease. Whilst…
Introduction One of the most important public health concerns is the ever-growing problem of antibiotic resistance. Importantly, the rate at which new molecules are introduced into clinical practise has slowed…