Efficacy and safety of intravenous fosfomycin for the treatment of difficult-to-treat Gram-negative bacterial infections

Introduction While many antimicrobial classes and compounds are potent in vitro, they may be accompanied with excessive toxicity or poor pharmacokinetics, limiting their clinical value in specific situations. As a…

Continue ReadingEfficacy and safety of intravenous fosfomycin for the treatment of difficult-to-treat Gram-negative bacterial infections

An Update on Eight “New” Antibiotics against Multidrug-Resistant Gram-Negative Bacteria

Introduction Gram-negative bacteria cause two-thirds of infections in intensive care units (ICUs), and antibiotic resistance among these bacteria is a serious issue. Several multidrug-resistant Gram-negative bacteria, including carbapenem-resistant Acinetobacter baumannii,…

Continue ReadingAn Update on Eight “New” Antibiotics against Multidrug-Resistant Gram-Negative Bacteria