Introduction Critical care ultrasound (CCUS) is widely accepted in the field of critical care medicine as a valuable tool in the intensive care unit and emergency department. It plays a…
Introduction Invasive aspergillosis (IA) is an acute infection affecting patients who are immunocompromised, as a result of receiving chemotherapy for malignancy, or immunosuppressant agents for transplantation or autoimmune disease. Whilst…
Introduction Invasive fungal infections are an important cause of morbidity and mortality, especially in critically ill patients Increasing resistance rates and inadequate antifungal exposure have been documented in these patients,…
Background Fungal infections are a major problem affecting over one billion people annually. Emerging pathogens and increasing resistance rates are complicating the situation, while new therapeutic options remain slow to…
Introduction A significant source of morbidity and mortality in haematological patients, particularly those undergoing hematopoietic stem cell transplantation (HSCT), is invasive fungal diseases (IFD). Due to non-specific symptoms and a…
Introduction Invasive fungal diseases (IFDs) present an increasing global burden in immunocompromised and other seriously ill populations. Early diagnosis encompassing accurate detection and identification of the causative agent and of…
Introduction As at-risk populations grow, invasive fungal infections keep rising. The high morbidity and mortality rates associated with fungal diseases require ongoing research into novel antifungal agents and diagnostic techniques…
Introduction Direct damage to airway epithelium and immune dysregulation in severe viral pneumonia along with treatment with immunosuppressive agents is known to cause increased susceptibility to fungal superinfections, such as…
Introduction The treatment of invasive fungal infections in liver transplant recipients is difficult because they are linked to increased morbidity and mortality. Despite a lack of clinical evidence, antifungal combination…
Introduction One of the most important public health concerns is the ever-growing problem of antibiotic resistance. Importantly, the rate at which new molecules are introduced into clinical practise has slowed…