Novel Therapeutic Approaches to Invasive Candidiasis: Considerations for the Clinician

Introduction In-hospital morbidity and mortality continue to be significantly impacted by invasive candidiasis (IC), a condition caused by the yeast pathogen Candida. The emergence of multi-resistant Candida species, including Candida…

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Nanotechnology-Based Approaches for Voriconazole Delivery Applied to Invasive Fungal Infections

Introduction Fungal infections are a growing threat to global public health, with some species causing life-threatening illnesses. Immunocompromised patients are at higher risk, and systemic fungal infections can be fatal…

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Robots and Intelligent Medical Devices in the Intensive Care Unit: Vision, State of the Art and Economic Analysis

Introduction Robotics is frequently regarded as a crucial enabling technology for tomorrow's society. This study looks at how robotics and intelligent medical devices (IMD) are used in intensive care. The…

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Intensive Care Unit Physicians’ Perspectives on Artificial Intelligence–Based Clinical Decision Support Tools: Preimplementation Survey Study

Introduction Artificial intelligence–based clinical decision support (AI-CDS) tools to enhance personalized medicine is on the rise. In the ICU, complex and high-stakes decisions are made that might benefit from data-driven…

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Utility of plasma cell-free DNA next-generation sequencing for diagnosis of infectious diseases in patients with hematological disorders

Introduction Infection is one of the most common complications for patients with neutropenia and can lead to high mortality if inappropriate empirical antibiotic treatment is administered. Accurate and timely pathogen…

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Carbapenem-resistant gram-negative bacterial infection in intensive care unit patients: Antibiotic resistance analysis and predictive model development

Introduction The overuse of carbapenem antibiotics has resulted in an increase in carbapenem-resistant gram-negative bacterial infections, posing a significant public health threat. These infections are prevalent in intensive care units…

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Diagnosis and management of fungal infections in solid organ transplant recipients in South Asia

Introduction Solid organ transplant (SOT) recipients in South Asia frequently contract fungi infections. After urinary tract infections and tuberculosis, invasive fungal infections (IFI) are the third most frequent cause of…

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New Drugs for the Treatment of Pseudomonas aeruginosa Infections with Limited Treatment Options: A Narrative Review

Introduction One of the most dangerous organisms that cause major hospital acquired infections is P. aeruginosa. It is naturally resistant to many antimicrobial treatments, and the management of such infections…

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