Abstract According to the World Health Organization (WHO), 10.0 million people worldwide contracted tuberculosis (TB) in 2019, with 1.4 million people dying from the disease. Multidrug-resistant tuberculosis is caused by…
Introduction In today's medical critical care unit, point-of-care ultrasonography (POCUS) has become a standard of treatment (ICU). POCUS's position in the medical ICU has expanded sequentially during the last three…
Introduction While many antimicrobial classes and compounds are potent in vitro, they may be accompanied with excessive toxicity or poor pharmacokinetics, limiting their clinical value in specific situations. As a…
Introduction Gram-negative bacteria cause two-thirds of infections in intensive care units (ICUs), and antibiotic resistance among these bacteria is a serious issue. Several multidrug-resistant Gram-negative bacteria, including carbapenem-resistant Acinetobacter baumannii,…
Introduction Clinical imaging has a role in early identification and helps guide additional testing in patients with suspected Invasive fungal diseases (IFD). While the presence of particular lesions may raise…
Introduction The alarmingly rising rates of sepsis and septic shock, as well as the related mortality, morbidity, and yearly treatment expenditures among ICU patients, are a growing source of worry.…
Introduction Over the past 20 years or so, invasive fungal diseases (IFDs) have become one of the main causes of death in hematological patients treated with high-intensity chemotherapy and/or a…
Introduction Cryptococcus neoformans is a life-threatening invasive fungal disease. It is more than merely a multi-organ infection; the fungus' intracellular survival and extracellular proliferation play essential roles in the pathophysiology…
Introduction The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic, putting enormous strain on healthcare systems around the world. Depending on the admission criteria and available resources,…
Introduction Bacterial infections and sepsis cause major morbidity and death in patients hospitalised to the intensive care unit, and their management is complicated by the rise in antibiotic resistance worldwide.…