Extracorporeal blood purification therapies for sepsis-associated acute kidney injury in critically ill patients: expert opinion from the SIAARTI-SIN joint commission

Introduction Sepsis-Associated Acute Kidney Injury (SA-AKI) is a critical condition with high morbidity and mortality in intensive care unit patients. Extracorporeal blood purification therapies have been developed for managing sepsis…

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The “CHEOPS” bundle for the management of Left Ventricular Diastolic Dysfunction in critically ill patients

Introduction Left ventricular diastolic dysfunction (LVDD) significantly impacts the outcomes of critically ill patients in the intensive care unit. Although LVDD assessment is crucial, treatment options are limited, and there…

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Role of nebulized colistin as a substitutive strategy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective cohort study

Introduction Nosocomial pneumonia caused by carbapenem-resistant Gram-negative bacteria (CR-GNB) is a growing concern worldwide due to limited treatment options and poor prognosis. VAP-prevention strategies have recently been grouped together into…

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Aerosolized Antibiotics to Manage Ventilator-Associated Infections: A Comprehensive Review

Introduction Critically ill patients on ventilators are prone to lower respiratory tract infections, ranging from tracheal tube colonization to ventilator-associated tracheobronchitis (VAT) and ventilator-associated pneumonia (VAP). VAP is associated with…

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A multisite evaluation of antifungal use in critical care: implications for antifungal stewardship

Introduction ICUs are settings of high antifungal consumption. Excessive antifungal use may cause individual and collective harm due to treatment-related adverse effects, drug–drug interactions and the selection of drug-resistant fungi,…

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Ceftazidime-avibactam, meropenem-vaborbactam, and imipenem-relebactam activities against multidrug-resistant Enterobacterales from United States Medical Centers (2018–2022)

Introduction Treatment options for infections caused by multidrug- resistant (MDR) Enterobacterales are limited and these infections are associated with high clinical failure and mortality rates, especially in vulnerable patients. In…

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The use of smart environments and robots for infection prevention control: A systematic literature review

Introduction Infection prevention and control (IPC) is essential to prevent nosocomial infections. This manuscript aims at investigating the current use and role of robots and smart environments on IPC systems…

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