Introduction Invasive fungal infections (IFIs) pose a significant threat to critically ill children, particularly those with compromised immune systems. Among the most prevalent fungal pathogens are species of Candida, Aspergillus,…
Introduction Nosocomial pneumonia, encompassing hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), is a major cause of mortality among critically ill patients. A growing number of cases are attributed to multi-drug-resistant…
Introduction (Article introduction authored by ICU Editorial Team) Invasive fungal infections, particularly those caused by moulds, pose significant morbidity and mortality risks. Limited antifungal classes suffer from toxicities and increasing…
Introduction (Article introduction authored by ICU Editorial Team) Pulmonary invasive fungal infections (pIFI) disproportionately affect patients with hematological malignancies (HM), primarily due to their underlying disease and intensive chemotherapy-induced neutropenia.…
Introduction (Article introduction authored by ICU Editorial Team) In critically ill patients with acute respiratory failure, thoracic imaging plays a crucial role in evaluating disease nature, extent, and progression, guiding…
Introduction (Article introduction authored by ICU Editorial Team) Treatments for rare and emerging invasive fungal diseases (IFDs) are urgently needed. Diseases such as mucormycosis, hyalohyphomycosis, and phaeohyphomycosis occur less frequently…
Introduction (Article introduction authored by ICU Editorial Team) Sepsis, characterized by life-threatening organ dysfunction due to a dysregulated host response to infection, affects millions worldwide annually and carries a high…
Introduction (Article introduction authored by ICU Editorial Team) Since the advent of intensive care units in the twentieth century, several advances have been developed in relation to diagnosis, organ support,…
Introduction (Article introduction authored by ICU Editorial Team) In recent years, the prevalence of hospital-acquired infections caused by carbapenem-resistant Gram-negative bacteria (CRGNB) has increased globally, posing significant threats to patient…
Introduction (Article introduction authored by ICU Editorial Team) Nosocomial CNS infections with carbapenem- and colistin-resistant Gram-negative and vancomycin-resistant Gram-positive bacteria present a growing therapeutic challenge. This review examines the pharmacokinetics,…