Introduction Intelligent health applications are being developed using automation technology to help patients by providing smart health solutions. The proposed research aims to create an intelligent automated hospital infrastructure capable…
Introduction In patients with underlying chronic lung disease, the prevalence of fungal infection is rising. The environmental mould Aspergillus fumigatus, as well as other filamentous fungi, are primarily responsible for…
Introduction Triazole antifungals like voriconazole, posaconazole, and isavuconazole are used to treat invasive fungal infections like pulmonary aspergillosis. Triazoles inhibit cytochrome P450 enzymes (CYP450) and cause fungal cell death by…
Introduction The International Guidelines for Management of Sepsis and Septic Shock 2021 and the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 share a common issue…
Introduction Numerous testing advances have benefitted the study of infectious illnesses, beginning with the first light microscope in 1716, followed by Koch's Postulates in 1890, and, most recently, the discovery…
Introduction Infections caused by fungi can be important causes of morbidity and mortality in certain patient populations, including those who are highly immunocompromised or critically ill. Invasive mycoses can be…
Introduction Despite advancements in antifungal therapy over the last two decades, invasive fungal infections (IFIs) continue to be a major cause of morbidity and mortality among immunocompromised patients, particularly if…
Introduction Surgical site infections (SSIs) are common postoperative complications caused by community or hospital-acquired bacteria, as well as other endogenous opportunistic germs, contaminating the surgical wound or implanted medical equipment.…
Introduction This review highlights emerging fungal infections, including newly described species, such as Candida auris, and those that having undergone taxonomic classification and were previously known by other names, including…
Introduction Heme-containing peroxidases are widely distributed in the animal and plant kingdoms and play an important role in host defense by generating potent oxidants. Myeloperoxidase (MPO), the prototype of heme-containing…