Corticosteroids in Sepsis and Septic Shock: A Systematic Review, Pairwise, and Dose-Response Meta-Analysis

Introduction (Article introduction authored by ICU Editorial Team) The utilization of corticosteroids in the management of sepsis and septic shock has remained contentious despite extensive examination through randomized controlled trials…

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Micromotor-based dual aptassay for early cost-effective diagnosis of neonatal sepsis

Introduction (Article introduction authored by ICU Editorial Team) Improving sepsis diagnosis in newborns, given their extended life expectancy, is paramount, yet early detection remains a significant challenge. However, a breakthrough…

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Clinical recommendations for the inpatient management of lower respiratory tract infections in children and adolescents with severe neurological impairment

Introduction (Article introduction authored by ICU Editorial Team) Children and adolescents with severe neurological impairment (SNI) face complex medical challenges, often experiencing severe and recurrent lower respiratory tract infections (LRTIs).…

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Management of Bacterial and Fungal Infections in the ICU: Diagnosis, Treatment, and Prevention Recommendations

Introduction (Article introduction authored by ICU Editorial Team) Bacterial and fungal infections are prevalent among intensive care unit (ICU) patients, with up to 50% diagnosed at any given time. These…

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Extracorporeal blood purification therapies for sepsis-associated acute kidney injury in critically ill patients: expert opinion from the SIAARTI-SIN joint commission

Introduction Sepsis-Associated Acute Kidney Injury (SA-AKI) is a critical condition with high morbidity and mortality in intensive care unit patients. Extracorporeal blood purification therapies have been developed for managing sepsis…

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The “CHEOPS” bundle for the management of Left Ventricular Diastolic Dysfunction in critically ill patients

Introduction Left ventricular diastolic dysfunction (LVDD) significantly impacts the outcomes of critically ill patients in the intensive care unit. Although LVDD assessment is crucial, treatment options are limited, and there…

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