Introduction Clinical imaging has a role in early identification and helps guide additional testing in patients with suspected Invasive fungal diseases (IFD). While the presence of particular lesions may raise…
Introduction The alarmingly rising rates of sepsis and septic shock, as well as the related mortality, morbidity, and yearly treatment expenditures among ICU patients, are a growing source of worry.…
Introduction Over the past 20 years or so, invasive fungal diseases (IFDs) have become one of the main causes of death in hematological patients treated with high-intensity chemotherapy and/or a…
Introduction Cryptococcus neoformans is a life-threatening invasive fungal disease. It is more than merely a multi-organ infection; the fungus' intracellular survival and extracellular proliferation play essential roles in the pathophysiology…
Introduction The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic, putting enormous strain on healthcare systems around the world. Depending on the admission criteria and available resources,…
Introduction Bacterial infections and sepsis cause major morbidity and death in patients hospitalised to the intensive care unit, and their management is complicated by the rise in antibiotic resistance worldwide.…
Introduction Voriconazole is one of the first-line therapies for invasive pulmonary aspergillosis. Many factors, such as drug-drug interactions (DDIs), erratic absorption, and continuous renal replacement therapy (CRRT), influence voriconazole exposure,…
Introduction Candida glabrata is a new Candida species that causes infections ranging from minor to life-threatening systemic illness. Echinocandins and azoles are commonly employed as first-line therapy to treat C.…
Abstract In a resource-limited country like India, rationing of scarce critical care resources might be required to ensure appropriate delivery of care to the critically ill patients suffering from COVID-19…
Introduction Emerging data are now surfacing suggesting that recombinant protein vaccines indeed might offer an advantage or complement to the nucleic acid or viral vector vaccines that will likely reach…