Introduction (Article introduction authored by ICU Editorial Team) In recent years, the prevalence of hospital-acquired infections caused by carbapenem-resistant Gram-negative bacteria (CRGNB) has increased globally, posing significant threats to patient…
Introduction (Article introduction authored by ICU Editorial Team) The utilization of corticosteroids in the management of sepsis and septic shock has remained contentious despite extensive examination through randomized controlled trials…
Introduction (Article introduction authored by ICU Editorial Team) Sepsis, a harmful response to infection, can lead to life-threatening organ dysfunction, with sepsis-associated acute kidney injury (SA-AKI) being the most common…
Introduction (Article introduction authored by ICU Editorial Team) Difficult-to-treat pulmonary infections caused by multidrug-resistant (MDR) pathogens are a global concern due to increasing incidence and high morbidity/mortality. Nebulized antibiotics are…
Introduction Nosocomial pneumonia caused by carbapenem-resistant Gram-negative bacteria (CR-GNB) is a growing concern worldwide due to limited treatment options and poor prognosis. VAP-prevention strategies have recently been grouped together into…
Introduction Critically ill patients on ventilators are prone to lower respiratory tract infections, ranging from tracheal tube colonization to ventilator-associated tracheobronchitis (VAT) and ventilator-associated pneumonia (VAP). VAP is associated with…
Introduction ICUs are settings of high antifungal consumption. Excessive antifungal use may cause individual and collective harm due to treatment-related adverse effects, drug–drug interactions and the selection of drug-resistant fungi,…
Introduction Infection is one of the most common complications for patients with neutropenia and can lead to high mortality if inappropriate empirical antibiotic treatment is administered. Accurate and timely pathogen…
Introduction The overuse of carbapenem antibiotics has resulted in an increase in carbapenem-resistant gram-negative bacterial infections, posing a significant public health threat. These infections are prevalent in intensive care units…
Introduction Invasive fungal infections are an important cause of morbidity and mortality, especially in critically ill patients Increasing resistance rates and inadequate antifungal exposure have been documented in these patients,…