Introduction Invasive candidiasis is a serious fungal infection seen in 2–10% of ICU patients, driven by Candida species that can enter the bloodstream, form biofilms, and spread to multiple organs.…
Introduction Pneumonia is common and potentially fatal, with CAP causing high hospitalizations and significant mortality. Its economic burden is substantial, and HAP/VAP further increase mortality, hospital stay, and cost. Multiple…
Introduction The studies presented in this issue collectively underscore the growing potential of novel peptides as foundations for next-generation antibacterial agents—especially in the context of rising antibiotic resistance. Increasingly, new…
Introduction Lower respiratory tract infections (LRTIs) cause millions of deaths globally each year and remain a major health and economic burden, especially in low- and middle-income countries. They are classified…
Introduction Leptospiros is thought to be the most widespread zoonosis in the world. A systematic review estimated that there are more than one million cases worldwide, with nearly 60 000…
Introduction Sepsis remains a major global health challenge due to its complexity and delayed recognition. Artificial intelligence (AI) shows promise in improving early detection, risk prediction, and personalized treatment using…
Introduction Sepsis is a life-threatening condition, and fungal pathogens are an increasingly important cause, especially in high-risk groups. During COVID-19, fungal co-infections gained significant attention due to their high morbidity…
Introduction Sepsis is a critical medical emergency caused by an uncontrolled immune response to infection, resulting in organ dysfunction. It continues to be a major global health challenge with high…
Introduction Antimicrobial resistance (AMR) is a major global health threat. According to the CDC (2019), over 2.8 million antibiotic-resistant infections and 35,000 deaths occur annually in the U.S., rising to…
Introduction Antibiotic-resistant bacteria are a growing global threat, causing longer hospital stays, higher costs, and increased mortality. The rise of multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacteria—such as…