New β-Lactam/β-Lactamase Inhibitor Combination Antibiotics

Introduction The rise of antimicrobial resistance, especially among Gram-negative bacteria, has led to the development of new β-lactam/β-lactamase inhibitor (BL/BLI) combinations. Recently approved agents—cefepime/enmetazobactam, aztreonam/avibactam, and sulbactam/durlobactam—target resistant pathogens like…

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Nosocomial lower respiratory tract infections in patients with immunosuppression: a cohort study

Introduction This post-hoc analysis of a multinational ICU study assessed and compared the clinical profiles, microbiological findings, and outcomes of immunosuppressed versus non-immunosuppressed patients with nosocomial lower respiratory tract infections…

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